Impact of antiresorptive drugs on dental implant success rate- a systematic review
항흡수제 복용이 치과 임플란트 성공에 미치는 영향에 대한 연구 -체계적 문헌고찰
- 주제(키워드) 도움말 antiresorptive drug , dental implant success rate , systematic review
- 발행기관 강릉원주대학교 일반대학원
- 지도교수 도움말 박영욱, 김민근
- 발행년도 2024
- 학위수여년월 2024. 2
- 학위명 석사
- 학과 및 전공 도움말 일반대학원 치의학과
- 세부분야 해당없음
- 실제URI http://www.dcollection.net/handler/kangnung/000000011599
- UCI I804:42001-000000011599
- 본문언어 영어
초록/요약 도움말
Antiresorptive drugs, such as bisphosphonates and denosumab, are widely used for osteoporosis and cancer-related conditions. As patients receving antiresorptive therapy are increasing, oral and maxillofacial surgeons are aware of potential implications like medication-related osteonecrosis of the jaw (MRONJ) after dental surgery like implant placements. Objective: This systematic review aimed to evaluate the impact of antiresorptive drugs on dental implant success rate, and to suggest guidelines for dental implant placement in patients under antiresorptive therapies. Methods: An electrical search was conducted in databases such as PubMed and Cochrane, followed by Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. The review included studies from 2014 march, focusing on various study designs like randomized control studies, cohort studies, and case series. Results: In a total of 196 articles, based on inclusion criteria, 9 articles were selected. The dental implant success rates across the studies ranged from 36.2% to 100%. A notable association was identified between the dosage and administration route of antiresorptive drugs and dental implant success rates. Additionally, presence of dental implant could be potential risk for medication-related osteonecrosis of the jaw (MRONJ) onset in patients under antiresorptive therapy. Conclusion: Low dose and oral administration of antiresorptive drugs seem to present a lower risk of dental implant failure. A multidisciplinary approach is important when considering dental implants for patients on antiresorptive therapy. Further research is required to refine clinical practive guidelines for enhanced patient safety and better outcomes in dental implantology.
more목차 도움말
Ⅰ. Introduction 1 page
Ⅱ. Materials and Methods 4 page
1. Eligibility criteria 4 page
2. Information sources 4 page
3. Search strategy 4 page
4. Selection process 5 page
5. Data collection process 5 page
6. Data items 5 page
7. Study risk bias of assessment 5 page
Ⅲ. Results 7 page
Ⅳ. Discussion 9 page
Ⅴ. Conclusion 19 page
Ⅵ. Tables and Figures 21 page
Ⅶ. Reference 25 page
Ⅷ. 국문 초록 30 page
