검색 상세

The efficiency of mandible reconstruction with either 3-dimensional customized implant or reconstruction plate on an animal model

동물 실험모델에서 3차원적인 개별 매식물을 사용한 하악골 결손부의 재건과 재건용 금속판을 사용한 재건의 효과

  • 홍도 지아 캉 (Hong Do Gia Khang, Gangneung-Wonju National University, Department of Oral & Maxillofacial Surgery)

초록/요약 도움말

Introduction: The primary aims of this study was to compare the efficiency of a customized implant (CI) and reconstruction plate (RP) in the reconstruction of mandibular defect on an animal model regarding recovery based on daily food intake amount (DFIA) and screws status. The secondary aim of this study was to investigate whether more recent of cone beam computed tomography (CBCT) data could provide with better-improved precision for manufacturing specific CI. Material and method: For the animal experiment, 15 rabbits were acquired randomly and assigned to one of two groups. The RP group (control group, n=5) would receive a 5-hole mini-plate without any bone graft for reconstruction of the mandibular defect while the CI group (experimental group, n=10) would have their defect reconstructed by a CI instead. The CI group was then divided into two sub-groups: the 6-week CI (6WCI) group and the 1-week CI (1WCI) group. The difference between these two sub-groups was the amount of time from CI finishing to the reconstruction surgery (6 weeks vs. 1 week). The 6WCI group used the CBCT data taken 6 weeks before surgery for the manufacturing of CI while the CBCT data for the 1WCI group was taken at 1 week before the surgery. Postoperatively, DFIA was measured for 76 days until sacrifice. Radiographic images were also acquired to evaluate screw quantity. CBCT was taken after sacrificing for evaluation of screw status. Histological examination was performed in the CI group after the sacrifice. Result: The 1WCI group showed the highest value in both peak average recovery rate and fastest average recovery rate. There was a statistically significant difference between the average days required for 50% recovery of the 6WCI, 1WCI and RP groups (P=0.002). However, there were no statistically significant differences between the average days required for 80% recovery of each group. The difference between 6WCI group and RP group in term of reaching 50% recovery was statistically significant (P=0.035). There is a statistical difference between 6WCI group and 1WCI group in 50% recovery (P=0.001). Seven screws were lost during the observation time in the 6WCI group. Of all groups, the 1WCI groups showed the highest percentage of intact screws (94.29%). One rabbit in 6WCI group showed instability of CI at sacrifice. The new bone formation was observed in the CI group on CBCT as well as histological examination. Conclusion: Rabbits with mandibular defects treated with CI for reconstruction showed higher and faster recovery of the DFIA than those treated with a 5-hole mini-plate without bone graft. The CIs which are manufactured based on a more recent of CBCT data would result in more favorable screw status.

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목차 도움말

Ⅰ. Introduction ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 1
Ⅱ. Materials and methods ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 6
Ⅲ. Results ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 12
Ⅳ. Discussion ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 16
Ⅴ. Conclusion ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 23
Ⅵ. References ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 24
Ⅶ. Figure legends ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 30
Tables and Figures ∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙∙ 32

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