Streptococcus mutans biofilm에 대한 광역동 치료의 최적조건에 관한 연구
The optimum parameters for the antimicrobial potential of photodynamic therapy to Streptococcus mutans biofilms
- 주제(키워드) 도움말 photodynamic therapy , erythrosine , halogen curing unit , concentration of erythrosine , irradiation time of light , treatment time of erythrosine.
- 발행기관 강릉원주대학교 일반대학원
- 지도교수 朴好遠
- 발행년도 2014
- 학위수여년월 2014. 8
- 학위명 박사
- 학과 및 전공 일반대학원 치의학과
- 세부전공 소아 청소년치과학 전공
- 원문페이지 21 p.
- 실제URI http://www.dcollection.net/handler/kangnung/000000006452
- 본문언어 한국어
초록/요약
Purpose: The purpose of our study was to evaluate the photodynamic therapy (PDT) effects of a combination of erythrosine and a standard dental halogen curing unit on viability of S. mutans in the biofilm phase. Methods: To investigate the optimum treatment parameters, we compared the effects of PDT by concentration of erythrosine, irradiation time of light and treatment time of erythrosine. Results: 1. The higher concentration of erythrosine (0, 10, 20, 40, 80 µmol·L-1) in the presence of light irradiation induced greater effects in reduction of viability of S. mutans. There was statistically significant difference in 20, 40, 80 µmol·L-1. 2. The higher irradiation time of light (0, 5, 15, 30, 60, 75s) in the presence of erythrosine induced greater effects in reduction of viability of S. mutans. There was statistically significant difference in 30, 60, 75seconds. 3. The higher treatment time of erythrosine(0, 1, 2.5, 5min) in the presence of erythrosine induced greater effects in reduction of viability of S. mutans. There was statistically significant difference in 2.5, 5 minutes. Conclusion: The results of our study proved PDT on S. mutans using erythrosine and the dental halogen curing unit conventionally used in dental clinics is effective in the condition of erythrosine concentration 20-40 µmol·L-1 , irradiation time over 30 seconds, erythrosine treatment time over 2,5 minutes.
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