우렁쉥이 및 해삼의 건강기능활성 효능에 대한 연구
Studies on Health Functional Activities of Ascidian and Sea Cucumber
- 발행기관 江陵大學校 産業大學院
- 지도교수 조순영
- 발행년도 2007
- 학위수여년월 2007. 8
- 학위명 석사
- 학과 및 전공 食品科學科
- 원문페이지 viii, 33 p.
- 본문언어 한국어
초록/요약
The purpose of this study was to verify the health functional activities such as antidiabetes and antihyperlipidemias in ascidian(Halocynthia roretzi) and sea cucumber(Stichopus japonicus Selenka) by in vivo animal test. 1. The ascidians (meat and tunic) and sea cucumbers (whole body) for this study had 84~93% in water content. And It was very fresh as less than 10mg% level in Volatile basic nitrogen(VBN) values of the ascidians and sea cucumbers. The composition of meat of ascidian was fairly. The tunic of ascidian had high percent of ash. The sea cucumber had high percent of ash and protein. 2. The rats were fed dried ascidian and sea cucumber with oral needle jonde for 4 weeks. The blood sugar level was decreased in more feeding in longer feeding. The tunic of ascidian decreased blood sugar level more than the muscle. And the sea cucumber decreased blood sugar level more than the ascidian. 3. In the case of hyperlipidemia was induced by poloxamer 407, the values of total cholesterol and triglyceride had no significant differences to reference sample but the tunic of ascidian had small differences. However, in the case of triton WR-1339 injection, there were significant results. Especially, the tunic of ascidian had very significant results compared to control sample triton WR-1339 injected only. The rats had been fed 200mg/kg Dose of the tunic of ascidian for 4weeks, and the triglyceride was in rat blood decreased less than 20.9% and total cholesterol decreased less than 24.4%. From the above results, the tunic of ascidian and the sea cucumber are supposed to be a good health functional food for antidiabetes and antihyperlipidemias.
more목차
Ⅰ. 서 론 = 1
Ⅱ. 재료 및 방법 = 6
1. 실험재료 = 6
2. 실험방법 = 8
1) 일반 성분 분석 및 신선도 측정 = 8
① 일반 성분 분석 = 8
② 휘발성 염기 질소(VBN) 함량 측정 = 8
2) 건조시료의 제조 = 9
3) 동물 실험을 통한 항당뇨 검증 시험 = 10
① 실험동물, 사육조건, 실험균의 구성 = 10
② 동물 Model = 10
③ 혈당 측정 방법 = 10
④ 통계처리 = 10
4) 동물 실험을 통한 항고지혈증 효능 검증 시험 = 10
① 실험동물, 사육조건, 실험군의 구성 = 10
② 동물 Model = 11
㉮ Poloxamer-407로 유발된 고지혈증 = 11
㉯ Triton WR-1339로 유발된 고지혈증 = 11
③ 혈중 지질함량의 측정 = 11
㉮ Total chlesterol 함량의 측정 = 11
㉯ Triglyceride 함량의 측정 = 11
④ 통계처리 = 12
Ⅲ. 결과 및 고찰 = 13
1. 시료의 수율 = 13
2. 우렁쉥이 및 해삼 시료의 신선도와 일반성분 = 14
3. 동물 식이 후 혈중 glucose 함량에 미치는 영향 = 17
4. 동물 식이 후 혈중 지질 함량에 미치는 영향 = 20
Ⅳ. 결론 및 요약 = 25
Ⅴ. 참고 문헌 = 26
